PerkinElmer

活體成像試劑

OF

PerkinElmer公司提供種類豐富的生物發光及熒光活體成像試劑,包括種類豐富的腫瘤發光細胞株、發光細菌、發光底物、慢病毒轉染試劑盒、功能性熒光探針、熒光染料、熒光標記試劑盒等,為您在進行疾病相關生物標志物及疾病通路研究中提供廣闊的應用選擇。

僅供科學研究,非臨床診斷用途。

產品與服務 (111)
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  • In vivo (1)
熒光劑類型
  • Targeted (20)
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  • Vascular (9)
  • Cell labeling (2)
顯像模式
  • Fluorescence (67)
  • Bioluminenscence (41)
  • Chemilumiluminescence (2)
  • Bioluminescence (1)
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  • XenoLight (25)
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1-12 的 111 產品與服務

  • In vivo Fluorescent Agents

    Neutrophil Elastase 680 FAST Fluorescent Imaging Agent

    Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications.?
  • In vivo Fluorescent Agents

    Genhance 680 Fluorescent Imaging Agent (5mg)

    Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications.?
  • RediJect Inflammation Probe Standard Kit

    XenoLight RediJect Chemiluminescent Inflammation Probe (Standard kit)

    XenoLight RediJect Inflammation probe is a chemiluminescent in vivo reagent for monitoring Inflammation. This probe is offered in a ready-to-use format and can be conveniently applied to study myeloperoxidase (MPO) activity of activated phagocytes.
  • RediJect 2-DG Fluorescent Imaging Probe (Standard kit)

    XenoLight RediJect 2-DeoxyGlucosone (DG) 750 is a fluorescent imaging probe for in vivo targeting of tumors that typically exhibit elevated glucose uptake rate in comparison to surrounding tissues. To achieve maximum glucose targeting and enhanced tumor uptake, the probe has been designed to contain four 2-DG molecules per dye molecule. ?
  • VivoTrack-680 Fluorescent Labeling Kit - Explorer Kit NEV12001

    VivoTrack 680 NIR Fluorescent Imaging Agent (Explorer kit)

    Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications.
  • XenoLight D-Luciferin K+ Salt

    XenoLight D-Luciferin - K+ Salt Bioluminescent Substrate

    Luciferin is essential in performing your bioluminescent assays, and the quality of your research will depend on the quality of your luciferin. Whether used to perform in vitro assays, or to monitor light production in vivo, PerkinElmer’s high quality luciferin is available at an affordable price.
  • S. aureus Bioluminescent Bacteria

    Staphylococcus aureus - Xen31

    Staphylococcus aureus - Xen31 bioluminescent pathogenic bacteria for in vivo and in vitro drug discovery. This product was derived from a parental strain from the American Type Culture Collection, used under license. Staph. aureus-Xen31 possesses a stable copy of the Photorhabdus luminescens lux operon on the bacterial chromosome.
  • In vivo Fluorescent Agents

    MMPSense Fluorescent Imaging Agent

    Matrix metalloproteinases (MMPs) are calcium-dependent zinc containing endopeptidases responsible for the degradation of most of extracellular matrix proteins during organogenesis, growth and normal tissue turnover. MMPs play a role in almost every biological cell process from embryo implantation to cell death and have been implicated in a wide range of diseases including inflammation, arthritis, pulmonary disease, cancer and more.

    PerkinElmer’s MMPSense NIR activatable fluorescence agents are designed to evaluate many disease related processes including cancer progression, rheumatoid arthritis, pulmonary disease and more as well as evaluating therapeutic efficacy of potential drug candidates.

  • Bioluminescent Oncology Cell Lines - Bioware

    Bioware? Brite Cell Line SKOV3 Red-FLuc

    Our bioluminescent light-producing oncology cell lines are labeled with luciferase or dual labeled with luciferase and fluorescent reporters (GFP) for in vivo studies.
  • In vivo Fluorescent Agents

    ProSense 750 FAST Fluorescent Imaging Agent

    Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications.?
  • S. aureus Bioluminescent Bacteria

    Staphylococcus aureus - Xen29

    Staphylococcus aureus - Xen29 bioluminescent pathogenic bacteria for in vivo and in vitro drug discovery. This product was derived from a parental strain from the American Type Culture Collection, used under license.?Staph. aureus-Xen29 possesses a stable copy of the Photorhabdus luminescens lux operon on the bacterial chromosome.
  • RediJect Control Kit

    RediJect 2-DG Fluorescent Imaging Probe (Control Dye)

    RediJect 2-DG control dye is a non-reactive dye that can be used as a negative control when using the RediJect 2-DG-750 fluorescent imaging probe. For laboratory use only. This product is intended for animal research only and not for use in humans.?
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Business Insights (5)
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1-5 的 5 Business Insights

  • 應用文獻

    Imaging Hepatocellular Liver Injury using NIR-labeled Annexin V

    Drug induced liver injury (DILI) is a major reason for late stage termination of drug discovery research projects, highlighting the importance of early integration of liver safety assessment in the drug development process. A technical approach for in vivo toxicology determination was developed using Acetaminophen (APAP), a commonly used over-the-counter analgesic and antipyretic drug, to induce acute hepatocellular liver injury.

  • 應用文獻

    Multiplex 2D Imaging of NIR Molecular Imaging Agents on the IVIS SpectrumCT and FMT 4000

    Epifluorescence (2D) imaging of superficially implanted mouse tumor xenograft models offers a fast and simple method for assessing tumor progression or response to therapy. This approach for tumor assessment requires the use of near infrared (NIR) imaging agents specific for different aspects of tumor biology, and this Application Note highlights the ease and utility of multiplex NIR fluorescence imaging to characterize the complex biology within tumors growing in a living mouse.

  • 應用文獻

    Vascular Imaging Probes For Oncology and Inflammation Using the IVIS Spectrum

    Optical-based in vivo imaging of vascular changes and vascular leak is an emerging modality for studying altered physiology in a variety of different cancers and inflammatory states. A number of fluorescent imaging probes that circulate with the blood, but have no target selectivity, have been used to detect tumor leakiness as an indication of abnormal tumor vasculature. Inflammation is also characterized by distinct vascular changes, including vasodilation and increased vascular permeability, which are induced by the actions of various inflammatory mediators. This process is essential for facilitating access for appropriate cells, cytokines, and other factors to tissue sites in need of healing or protection from infection. This application note investigates the use of three fluorescent imaging probes, to detect and monitor vascular leak and inflammation in preclinical mouse breast cancer models.

  • 應用文獻

    NIR Fluorescent Cell Labeling for In Vivo Cell Tracking (VivoTrack 680)

    Fluorescent dyes have been used for many years to label cells for microscopy studies, and a variety of dyes in the visible fluorescence spectrum are available to label different cellular compartments and organelles. Efficient delivery of the fluorophore to the cell without excessively modifying surface proteins or perturbing cell function is the major biotechnological challenge. In addition, researchers have taken on the challenge of in vivo imaging, focusing on near infrared (NIR) dyes that fluoresce in a spectral region better suited for in vivo imaging due to reduced background and higher tissue penetration.

  • 海報

    Combined efficacy & toxicity imaging following acute 5-FU treatment of HT-29 tumor xenografts

    Cancer chemotherapy can produce severe side effects such as suppression of immune function and damage to heart muscle, gastrointestinal tract, and liver. If serious enough, tissue injury can be a major reason for late stage termination of drug discovery research projects, so it is becoming more important to integrate safety/toxicology assessments earlier in the drug development process. There are a variety of traditional serum markers, tailored mechanistically to specific tissues, however there are no current non-invasive assessment tools that are capable of looking broadly at in situ biological changes in target and non-target tissue induced by chemical insult.

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