PerkinElmer

細胞遺傳學試劑 - 研究

OF

Fast, precise, and cost-effective targeted molecular karyotyping

BACs are Bacterial Artificial Chromosomes, large cloned sequences of human DNA typically 170,000 bases long. BAC probes have long been used for FISH. The BACs-on-Beads? technology uses probes generated from selected BACs immobilized onto Luminex? xMAP? encoded beads. The resulting bead sets are used to assay chromosomal gains and losses from minute sample amounts with high throughput. BACs-on-Beads analysis comprises hybridization of DNA sample sequences to BAC-derived probes representing the identified target regions. Samples are enzymatically labeled with biotin, and after hybridization in a 96-well plate a fluorescent streptavidin-phycoerythrin reporter is bound to the biotin label. Male and female reference DNA is also hybridized and the fluorescence ratio between each sample and reference DNA are compared to provide a clear display of any copy number changes in the targeted regions. Sample labeling is done enzymatically, which provides significant amplification of samples down to 100-200 ng.

For research use only. Not for use in diagnostic procedures.

產品與服務 (5)
Filters:

1-5 的 5 產品與服務

  • AutoDELFIA-B098-201-PAPP-A

    CGX Onco Arrays (outside USA) Onco (4 pack)

    CGX? Onco陣列是由Signature Genomics設計、開發和驗證的微陣列,專門用于白血病和淋巴瘤等造血系統疾病相關小基因畸變、以及實體瘤相關基因的檢測。
  • AutoDELFIA-B098-201-PAPP-A

    CGX Onco Arrays (outside USA) Onco (2 pack)

    CGX? Onco陣列是由Signature Genomics設計、開發和驗證的研究微陣列,專門用于白血病和淋巴瘤等造血系統疾病相關小基因畸變、以及實體瘤相關基因的檢測。
  • AutoDELFIA-B098-201-PAPP-A

    CGX Oligo Arrays (outside USA)

    CGX Oligo陣列是由Signature Genomics設計、開發和驗證的微陣列,專門用于研究應用中與學習障礙以及畸形特征相關小遺傳畸變的檢測。
  • AutoDELFIA-B098-201-PAPP-A

    KaryoLite BoBs? Kit

    KaryoLite BoBs*用于在單個分析中檢測全部24條染色體中臂特異性非整倍體,僅限研究用。產品涵蓋1-22號、X和Y所有染色體的p和q臂(近端著絲染色體中為q臂)
  • AutoDELFIA-B098-201-PAPP-A

    Constitutional BoBs??Kit

    產前 BoBsTM 用于檢測染色體非整倍體和基因微缺失.產前 BoBsTM 是一種簡便可靠的分析, 有著非常明顯的優點: 如樣本處理簡單, 所需樣本量小, 結果報告時間短, 相對于目前臨床應用的細胞遺傳學和分子遺傳學實驗的檢出率較高等
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